I'm Dr. Joshua Schwimmer, a nephrologist in New York City. • Kidney Notes was the first active nephrology blog, and The National Library of Medicine still uses Kidney Notes as an example of how to formally cite blogs in the medical literature. • Professionally, you can find me at Kidney.nyc. • Kidney Notes is for educational purposes only, not medical advice. Consult qualified health care professionals. See disclaimer.

Sunday, March 12, 2006

Glowing Mouse Hearts

Via Yahoo! News:
Researchers at Cornell University have created mice whose heart muscles are genetically engineered to fluoresce when the muscles contract. Junichi Nakai of the RIKEN Brain Science Institute in Wako-shi, Japan, developed the fluorescent molecule by modifying a green fluorescent protein (derived from bioluminescent jellyfish) and making it glow brightly enough to be observed in the working heart. The sensor molecule turns on and off like a switch in the presence of calcium; calcium concentrations in the muscle increase with each muscle contraction.
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